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Stop fRETting the Target: Next-Generation RET Inhibitors Have Arrived.

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BLU-667 is a next-generation RET inhibitor that maximizes on-target and minimizes off-target effects. It is an exemplar of genotype-driven drug development followed by multi-histology basket trial validation that is becoming… Click to show full abstract

BLU-667 is a next-generation RET inhibitor that maximizes on-target and minimizes off-target effects. It is an exemplar of genotype-driven drug development followed by multi-histology basket trial validation that is becoming a paradigm for precision oncology. Cancer Discov; 8(7); 797-9. ©2018 AACRSee related article by Subbiah et al., p. 836.

Keywords: generation ret; next generation; stop fretting; fretting target

Journal Title: Cancer discovery
Year Published: 2018

Link to full text (if available)


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