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In this issue of Cancer Discovery, Carrer and colleagues find that early events in pancreatic tumorigenesis are driven by altered acetyl-CoA metabolism, where targeting this axis in established cancer models… Click to show full abstract
In this issue of Cancer Discovery, Carrer and colleagues find that early events in pancreatic tumorigenesis are driven by altered acetyl-CoA metabolism, where targeting this axis in established cancer models impairs tumor growth. This work provides new insights into the roles of acetyl-CoA in pancreatic cancer and underscores the value of studying early events in carcinogenesis to yield new treatment strategies.See related article by Carrer et al., p. 416.
Keywords:
metabolism drives;
pancreatic tumors;
carcinogenesis maintenance;
cancer;
drives carcinogenesis;
maintenance pancreatic
Journal Title: Cancer discovery
Year Published: 2019
Link to full text (if available)
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Journal Title: Cancer discovery
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!