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SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

RNF113A methylation by SMYD3 improves alkylation damage response and impairs small cell lung cancer sensitivity to alkylation-based chemotherapy. Click to show full abstract

RNF113A methylation by SMYD3 improves alkylation damage response and impairs small cell lung cancer sensitivity to alkylation-based chemotherapy.

Keywords: lung cancer; rnf113a methylation; alkylation damage; small cell; cancer; cell lung

Journal Title: Cancer Discovery
Year Published: 2022

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