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Resistance of EGFR-mutant lung cancers to EGFR inhibitors can occur through engagement of mutation-prone DNA replication activated by GAS6 and AXL upregulation, and blocking this pathway can prevent resistance and… Click to show full abstract
Resistance of EGFR-mutant lung cancers to EGFR inhibitors can occur through engagement of mutation-prone DNA replication activated by GAS6 and AXL upregulation, and blocking this pathway can prevent resistance and offer new treatment strategies.
Keywords:
egfr mutant;
resistance offer;
mutant lung;
resistance;
prone dna;
dna replication
Journal Title: Cancer Discovery
Year Published: 2022
Link to full text (if available)
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Journal Title: Cancer Discovery
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!