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Pancreatic Neoplasms Are Frighteningly Common: A Role for Immune Surveillance?

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SUMMARY Carpenter and colleagues analyze organ donors to find that pancreatic intraepithelial neoplasia (PanIN), the precursor lesions of pancreatic ductal adenocarcinoma, are highly prevalent in the average healthy adult starting… Click to show full abstract

SUMMARY Carpenter and colleagues analyze organ donors to find that pancreatic intraepithelial neoplasia (PanIN), the precursor lesions of pancreatic ductal adenocarcinoma, are highly prevalent in the average healthy adult starting from a young age. Why these precursor lesions do not progress to cancer in most people is a mystery. See related article by Carpenter et al., p. 1324 (1).

Keywords: role immune; frighteningly common; neoplasms frighteningly; common role; immune surveillance; pancreatic neoplasms

Journal Title: Cancer discovery
Year Published: 2023

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