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Epigenomic Changes Prime PDAC Metastasis.

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Widespread chromatin modifications and DNA methylation could be responsible for inducing the spread of pancreatic ductal adenocarcinoma cells to distant sites, according to recent research. The findings also implicate glucose… Click to show full abstract

Widespread chromatin modifications and DNA methylation could be responsible for inducing the spread of pancreatic ductal adenocarcinoma cells to distant sites, according to recent research. The findings also implicate glucose metabolism as a driver of metastasis.

Keywords: epigenomic changes; changes prime; metastasis; prime pdac; pdac metastasis

Journal Title: Cancer discovery
Year Published: 2017

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