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Analysis Suggests Wider Use for PARP Inhibitors.

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Researchers have developed a new tool, HRDetect, to pinpoint tumors that display BRCA deficiency but don't harbor BRCA1/2 mutations. Evaluating their method in breast, ovarian, and pancreatic cancers, they identified… Click to show full abstract

Researchers have developed a new tool, HRDetect, to pinpoint tumors that display BRCA deficiency but don't harbor BRCA1/2 mutations. Evaluating their method in breast, ovarian, and pancreatic cancers, they identified patients whose tumors were potentially vulnerable to PARP inhibition but who didn't carry these mutations.

Keywords: parp inhibitors; use parp; wider use; analysis suggests; suggests wider

Journal Title: Cancer discovery
Year Published: 2017

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