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Indoximod Combo Triggers Responses in Melanoma.

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Adding the investigational IDO-pathway inhibitor indoximod to checkpoint inhibitor therapy resulted in a 52% overall response rate in patients with advanced melanoma enrolled in a phase II trial. The combination… Click to show full abstract

Adding the investigational IDO-pathway inhibitor indoximod to checkpoint inhibitor therapy resulted in a 52% overall response rate in patients with advanced melanoma enrolled in a phase II trial. The combination strategy has potential as an alternative for patients whose tumors do not respond to standard therapy.

Keywords: triggers responses; indoximod combo; combo triggers; responses melanoma

Journal Title: Cancer discovery
Year Published: 2017

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