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Alectinib Superior to Crizotinib for ALK+ NSCLC.

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Findings from the global phase III ALEX trial unequivocally show that alectinib is superior to crizotinib as first-line therapy for ALK+ non-small cell lung cancer. Alectinib more than doubled progression-free… Click to show full abstract

Findings from the global phase III ALEX trial unequivocally show that alectinib is superior to crizotinib as first-line therapy for ALK+ non-small cell lung cancer. Alectinib more than doubled progression-free survival, significantly reduced the incidence of brain and CNS metastases, and should be considered the new standard of care.

Keywords: crizotinib alk; alk nsclc; alectinib superior; superior crizotinib

Journal Title: Cancer discovery
Year Published: 2017

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