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Entinostat Helps Thwart Immunotherapy Resistance.

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Findings from the ENCORE-601 trial's melanoma cohort show that the experimental HDAC inhibitor entinostat is well tolerated and, together with pembrolizumab, induces durable responses in patients whose disease has progressed… Click to show full abstract

Findings from the ENCORE-601 trial's melanoma cohort show that the experimental HDAC inhibitor entinostat is well tolerated and, together with pembrolizumab, induces durable responses in patients whose disease has progressed on PD-1 blockade alone.

Keywords: entinostat helps; immunotherapy resistance; thwart immunotherapy; helps thwart

Journal Title: Cancer discovery
Year Published: 2019

Link to full text (if available)


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