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Drug Combo May Obviate Chemotherapy in ALL.

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A phase II trial shows that a chemotherapy-free regimen of dasatinib and blinatumomab produces molecular responses in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. The study found that 60% of… Click to show full abstract

A phase II trial shows that a chemotherapy-free regimen of dasatinib and blinatumomab produces molecular responses in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. The study found that 60% of patients had molecular responses after two cycles of blinatumomab and 71% had molecular responses after five cycles.

Keywords: molecular responses; combo may; obviate chemotherapy; may obviate; drug combo

Journal Title: Cancer discovery
Year Published: 2020

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