A three-drug regimen containing the CTLA4 inhibitor tremelimumab plus the PD-L1 inhibitor durvalumab and chemotherapy may be an effective first-line treatment strategy for patients with metastatic non-small cell lung cancer.… Click to show full abstract
A three-drug regimen containing the CTLA4 inhibitor tremelimumab plus the PD-L1 inhibitor durvalumab and chemotherapy may be an effective first-line treatment strategy for patients with metastatic non-small cell lung cancer. In the phase III POSEIDON trial, the combination significantly extended progression-free survival and overall survival compared with chemotherapy alone.
               
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