"A Small-Molecule Splicing Modulator Targets Spliceosome-Mutant Cells."

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The small molecule H3B-8800 binds to and modulates the SF3b complex to kill spliceosome-mutant cells. Click to show full abstract

The small molecule H3B-8800 binds to and modulates the SF3b complex to kill spliceosome-mutant cells.

Keywords: splicing modulator; mutant cells; molecule splicing; small molecule; spliceosome mutant

Journal Title: Cancer discovery
Year Published: 2018

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