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(R)-2HG Inhibits the BCAT Transaminase in IDH-Mutant Glioma.

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BCAT inactivation renders IDH-mutant cells dependent on glutaminase for glutamate and glutathione synthesis. Click to show full abstract

BCAT inactivation renders IDH-mutant cells dependent on glutaminase for glutamate and glutathione synthesis.

Keywords: bcat transaminase; 2hg inhibits; inhibits bcat; idh mutant; transaminase idh; mutant glioma

Journal Title: Cancer discovery
Year Published: 2018

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