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Selective γ-Secretase Inhibition Is a Potential Target for Leukemias.

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Targeting γ-secretase subunit PSEN1 blocks mutant NOTCH signaling in T-ALL without severe NOTCH toxicity. Click to show full abstract

Targeting γ-secretase subunit PSEN1 blocks mutant NOTCH signaling in T-ALL without severe NOTCH toxicity.

Keywords: potential target; selective secretase; inhibition potential; target leukemias; secretase; secretase inhibition

Journal Title: Cancer discovery
Year Published: 2019

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