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ARAF Mutations Limit Response to RAF Dimer Inhibition.

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Belvarafenib is active in BRAF- and NRAS-mutant tumors, but acquired ARAF mutations drive resistance. Click to show full abstract

Belvarafenib is active in BRAF- and NRAS-mutant tumors, but acquired ARAF mutations drive resistance.

Keywords: mutations limit; limit response; raf dimer; araf mutations; dimer inhibition; response raf

Journal Title: Cancer discovery
Year Published: 2021

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