Myc-driven B-cell lymphoma is demonstrated to induce selective and early TCR-independent metabolic suppression of CD4+ T cells. This process precedes changes to T-cell fate and function and occurs before significant… Click to show full abstract
Myc-driven B-cell lymphoma is demonstrated to induce selective and early TCR-independent metabolic suppression of CD4+ T cells. This process precedes changes to T-cell fate and function and occurs before significant changes in tumor burden.
               
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