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WTX 124 is an inducible IL-2 prodrug that is selectively activated in the tumor microenvironment. Administration of WTX-124 generates potent antitumor immunity by activating tumor-infiltrating lymphocytes while preventing the toxicity… Click to show full abstract
WTX 124 is an inducible IL-2 prodrug that is selectively activated in the tumor microenvironment. Administration of WTX-124 generates potent antitumor immunity by activating tumor-infiltrating lymphocytes while preventing the toxicity associated with systemic, high dose IL-2 treatment.
Keywords:
activated promotes;
promotes antitumor;
discovery conditionally;
immunity;
conditionally activated;
antitumor immunity
Journal Title: Cancer Immunology Research
Year Published: 2022
Link to full text (if available)
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Journal Title: Cancer Immunology Research
Year Published: 2022
Link to full text (if available)
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recommendations!