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The subcellular compartmentalization of Ras is regulated by interacting with intracellular CD59. CD59 deficiency results in reduced trafficking of Ras to the plasma membrane in T cells, thus inducing increased… Click to show full abstract
The subcellular compartmentalization of Ras is regulated by interacting with intracellular CD59. CD59 deficiency results in reduced trafficking of Ras to the plasma membrane in T cells, thus inducing increased T-cell signal transduction and antitumor activity.
Keywords:
ras compartmentalization;
regulated ras;
compartmentalization;
cd59;
cd59 regulated;
compartmentalization orchestrates
Journal Title: Cancer Immunology Research
Year Published: 2022
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Journal Title: Cancer Immunology Research
Year Published: 2022
Link to full text (if available)
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recommendations!