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Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer

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Galectin 4 is a cancer cell–produced protein abundant in pancreatic tumors. The data show that galectin 4 blocks antitumor immunity and identify galectin 4 as a potential novel drug target… Click to show full abstract

Galectin 4 is a cancer cell–produced protein abundant in pancreatic tumors. The data show that galectin 4 blocks antitumor immunity and identify galectin 4 as a potential novel drug target for treating pancreatic cancer.

Keywords: pancreatic cancer; galectin drives; drives immune; galectin; extracellular galectin; cancer

Journal Title: Cancer Immunology Research
Year Published: 2022

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