LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines

Photo by albertstoynov from unsplash

Greater understanding of immune-related adverse events (irAE) could lead to new approaches in overcoming them. The authors show immunopathology of irAE dermatitis is dominated by Th1/Tc1 TRM cells, suggesting topical… Click to show full abstract

Greater understanding of immune-related adverse events (irAE) could lead to new approaches in overcoming them. The authors show immunopathology of irAE dermatitis is dominated by Th1/Tc1 TRM cells, suggesting topical JAK inhibitors as corticosteroid-sparing agents in cutaneous irAEs.

Keywords: blockade induced; induced dermatitis; th1 tc1; dermatitis colitis; dermatitis; checkpoint blockade

Journal Title: Cancer Immunology Research
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.