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Influence of Adipose Tissue Distribution, Sarcopenia, and Nutritional Status on Clinical Outcomes After CD19 CAR T-cell Therapy

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This retrospective study demonstrates that the obesity paradox applies to patients receiving CAR T-cell therapy and that sarcopenia can exert long-lasting adverse effects on treatment responses. The data highlight use… Click to show full abstract

This retrospective study demonstrates that the obesity paradox applies to patients receiving CAR T-cell therapy and that sarcopenia can exert long-lasting adverse effects on treatment responses. The data highlight use of immuno-nutritional scores could aid in patient risk-stratification.

Keywords: car cell; influence adipose; cell therapy

Journal Title: Cancer Immunology Research
Year Published: 2023

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