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SWI/SNF Complex Genomic Alterations as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors in Multiple Cancers

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By analyzing all 31 SWI/SNF complex genes, the authors show SWI/SNF complex alterations are associated with improved clinical outcomes following immune checkpoint inhibitor (ICI) therapy across cancer types, suggesting that… Click to show full abstract

By analyzing all 31 SWI/SNF complex genes, the authors show SWI/SNF complex alterations are associated with improved clinical outcomes following immune checkpoint inhibitor (ICI) therapy across cancer types, suggesting that such alterations could serve as a prognostic biomarker for ICI therapy.

Keywords: biomarker; snf complex; swi snf; immune checkpoint

Journal Title: Cancer Immunology Research
Year Published: 2023

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