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Current Status and Treatment Strategies of Hemodialysis-Associated Pruritus.

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BACKGROUND Hemodialysis-associated pruritus (HAP) is often treatment-resistant, and is a serious comorbidity that adversely affects prognosis and reduces patient quality of life through sleep disruption and depression. SUMMARY HAP can… Click to show full abstract

BACKGROUND Hemodialysis-associated pruritus (HAP) is often treatment-resistant, and is a serious comorbidity that adversely affects prognosis and reduces patient quality of life through sleep disruption and depression. SUMMARY HAP can arise from a combination of several causes; accordingly, it is often resistant to treatment. HAP patients need the specific causes of their itching to be identified, with a comprehensive approach to treatment. We have implemented our own therapeutic algorithm, which covers cause specification, for HAP since June 2009. This resulted in a significantly decreased proportion of patients with itching (2016 vs. 2009: 77.3 vs. 96.6%), accompanied by a significant decrease in median visual analogue scale itching score (2016 vs. 2009: 21.0 vs. 53.0 mm), for patients treated for itching at our facility in October 2016. Key Messages: HAP patients need the causes of their itching to be specified, and to be treated with a comprehensive approach. Alleviation of itching is anticipated to improve patient quality of life and prognosis.

Keywords: associated pruritus; hap; treatment; current status; hemodialysis associated

Journal Title: Contributions to nephrology
Year Published: 2018

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