"Abstract 16292: Selective Platelet Protease-Activated-Receptor (PAR)1 and PAR4 Mediated Thrombin Desensitisation in the Elderly is Correlated With Inflammation and Chronic Thrombin Receptor Stimulation"

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Abstract 16292: Selective Platelet Protease-Activated-Receptor (PAR)1 and PAR4 Mediated Thrombin Desensitisation in the Elderly is Correlated With Inflammation and Chronic Thrombin Receptor Stimulation

Introduction: Platelet activation, by adenosine diphosphate (ADP) via P2Y12 receptors and thrombin via PAR1 and PAR4, is a key therapeutic target in cardiovascular disease (CVD). The efficacy of an... Click to show full abstract

Keywords: par4; 16292 selective; receptor; selective platelet; abstract 16292; platelet

Journal Title: Circulation
Year Published: 2020

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