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Biopsy-Proven Giant Cell Myocarditis Following the COVID-19 Vaccine

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iant cell myocarditis (GCM)—a rapidly progressive form of myocarditis—is a rare and potentially fatal diagnosis if not treated immediately. Endomyocardial biopsy is the gold standard for diagnosis. Treatment of GCM… Click to show full abstract

iant cell myocarditis (GCM)—a rapidly progressive form of myocarditis—is a rare and potentially fatal diagnosis if not treated immediately. Endomyocardial biopsy is the gold standard for diagnosis. Treatment of GCM involves immunosuppression along with symp-tomatic management of heart failure, arrhythmias, and the other cardiac sequelae of GCM. 1 We describe a case of GCM in a patient without cardiac history or significant comorbid conditions who presented with severe heart failure a few weeks after the BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech).

Keywords: myocarditis; cell myocarditis; covid vaccine; heart failure

Journal Title: Circulation. Heart Failure
Year Published: 2022

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