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Elming et al1 report that the efficacy of primary prevention implantable cardioverter-defibrillator (ICD) therapy is diminished among older participants of the DANISH trial (Danish Study to Assess the Efficacy of… Click to show full abstract
Elming et al1 report that the efficacy of primary prevention implantable cardioverter-defibrillator (ICD) therapy is diminished among older participants of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality), which randomized patients with nonischemic cardiomyopathy to ICD versus optimal medical therapy.2 In this secondary data analysis of the DANISH trial, ICD implantation was associated with a statistically significant improvement in survival among patients ≤70 years of age but not in those >70 years of age. This area of study is important because …
Journal Title: Circulation
Year Published: 2018
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