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A thermo-sensitive hydrogel based on Schiff base linkages with antioxidant property

Excessive oxidative stress leading to a consequently chronic inflammation remains a challenging problem for wound healing, and developing biomaterials with outstanding antioxidant property has great practical significance for wound treatment.… Click to show full abstract

Excessive oxidative stress leading to a consequently chronic inflammation remains a challenging problem for wound healing, and developing biomaterials with outstanding antioxidant property has great practical significance for wound treatment. Herein, a thermo-sensitive hydrogel based on Schiff base linkages (Cur@HBC/OHA) was prepared, and the physicochemical properties and antioxidant activities in vitro were investigated. The excellent biocompatibility, enhanced antibacterial activity and increased DPPH scavenging rate indicated that the prepared Cur@HBC/OHA hydrogel is a promising biomaterial for tissue engineering applications.

Keywords: hydrogel based; thermo sensitive; hydrogel; based schiff; antioxidant property; sensitive hydrogel

Journal Title: Materials Express
Year Published: 2024

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