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New (re)Purpose for an old drug: purinergic receptor blockade may extinguish the COVID-19 thrombo-inflammatory firestorm.

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Purinergic modulators, such as dipyridamole, target multiple pathways that have been implicated in COVID-19 pathogenesis, and thus the therapeutic benefit of these should be explored. Click to show full abstract

Purinergic modulators, such as dipyridamole, target multiple pathways that have been implicated in COVID-19 pathogenesis, and thus the therapeutic benefit of these should be explored.

Keywords: drug purinergic; old drug; receptor blockade; purpose old; purinergic receptor; new purpose

Journal Title: JCI insight
Year Published: 2020

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