LAUSR

We read the article “Monocyte to High-Density Lipoprotein Ratio Predicts Contrast-Induced Nephropathy in Patients With Acute Coronary Syndrome” with great interest. The authors found that monocyte to high-density lipoprotein ratio is higher in patients with acute coronary syndrome with contrast-induced nephropathy (CIN). Some agents can affect CIN. For example, several studies investigated the effect of N-acetylcysteine (NAC) on CIN and found contradictory results. Tepel et al reported a protective effect, while Durham et al found no effect. Huber et al showed that sodium bicarbonate and theophylline prevented CIN. Did Ulus et al use NAC, sodium bicarbonate, theophylline, or other agents? These agents could affect the interpretation of the study.