LAUSR

We read with interest the paper by Açar et al entitled “Association of Prediabetes With Higher Coronary Atherosclerotic Burden Among Patients With First Diagnosed Acute Coronary Syndrome.” They concluded that the coronary atherosclerosis burden is more advanced in prediabetics than in nondiabetics and is comparable between prediabetics and diabetics at first presentation of acute coronary syndrome (ACS). Ertem et al researched the relationship between Hemoglobin A1c (HbA1c) and Gensini score in patients with ACS. 2 They could not show any relation between HbA1c and Gensini scores. They showed relation between obesity and coronary atherosclerotic burden. In the study by Açar et al, there are no data about the association of obesity with coronary atherosclerotic burden. Their study population was nearly significantly composed by more males than females. Previously, Khaw et al showed that diabetes seems to be a more important risk factor in females than males in a long-term populationbased cohort in Caucasians living in Norfolk England. Açar et al showed no difference between diabetic and prediabetic subgroups in terms of Syntax and Gensini scores. However, they did not present the HbA1cvalues in the prediabetic and diabetic subgroups. We thought that Açar et al should have analyzed the comparison of HbA1c percentiles from the prediabetic and diabetic group and provide correlation graphs between HbA1c and Syntax and Gensini scores.