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Diagnostic challenge in veterinary pathology: Pruritus in a dog with a mixed cellular infiltrate

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An 11-year-old, castrated male German Shepherd dog initially presented with a 9-month history of pruritus and multifocal erythematous skin lesions, alopecia, and mild weight loss. Skin lesions waxed and waned… Click to show full abstract

An 11-year-old, castrated male German Shepherd dog initially presented with a 9-month history of pruritus and multifocal erythematous skin lesions, alopecia, and mild weight loss. Skin lesions waxed and waned without complete resolution and newer lesions developed in other body regions. Erythematous macules and alopecia began on the ventral abdomen and progressed to the chest and dorsum. The patient received 0.27 mg/kg cetirizine (twice daily for 20 days), 22 mg/kg amoxicillin/clavulanic acid twice daily for 20 days, 0.5 mg/kg oclacitinib (once daily for 30 days), and 6 mg/kg ketoconazole (once daily for 21 days), in the prior 5 months without significant improvement. There had been no changes in the dog’s appetite or water intake. A complete blood cell count and a serum biochemistry profile performed 3 months prior to referral revealed no abnormalities and thyroid hormone T4 was within the normal reference range.

Keywords: diagnostic challenge; veterinary pathology; pathology; pruritus; dog; daily days

Journal Title: Veterinary Pathology
Year Published: 2022

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