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The Effect of Methylphenidate Treatment on Olfactory Function in Children and Adolescents With ADHD.

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OBJECTIVE This study aimed to research whether there is an olfactory disorder in ADHD, and if so, what is the effect of methylphenidate on this condition. METHOD This is a… Click to show full abstract

OBJECTIVE This study aimed to research whether there is an olfactory disorder in ADHD, and if so, what is the effect of methylphenidate on this condition. METHOD This is a cross-sectional study aiming to evaluate olfactory threshold, identification, discrimination and threshold, discrimination, and identification (TDI) scores in 109 children and adolescents, 33 of whom have ADHD without medication, 29 with ADHD with medication and 47 control groups. RESULT In the post hoc tests, the mean odor discrimination test, the mean odor identification test, and the mean TDI scores of the unmedicated ADHD group were significantly lower than those of the other two groups, and that the mean odor threshold test scores of the medicated ADHD group were significantly lower than those of the control and unmedicated groups. CONCLUSION Olfactory function could be a useful tool to monitor treatment effects and may be a promising candidate as a biomarker in ADHD.

Keywords: olfactory; adolescents adhd; effect methylphenidate; children adolescents; olfactory function

Journal Title: Journal of attention disorders
Year Published: 2023

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