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Safety Assessment of Dimethiconol and Its Esters and Reaction Products as Used in Cosmetics

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Dimethiconol and its esters and reaction products are used in cosmetics as either skin-conditioning agents or hair-conditioning agents. The Cosmetic Ingredient Review (CIR) Expert Panel reviewed relevant data and concluded… Click to show full abstract

Dimethiconol and its esters and reaction products are used in cosmetics as either skin-conditioning agents or hair-conditioning agents. The Cosmetic Ingredient Review (CIR) Expert Panel reviewed relevant data and concluded that these ingredients are safe in the present practices of use and concentration described in this safety assessment. While there is an absence of data on reproductive and developmental toxicity and limited tumorigenicity and toxicokinetics data, the Panel reasoned that these ingredients would not be absorbed through the skin, obviating concern over potential reproductive and developmental toxicity or carcinogenicity.

Keywords: used cosmetics; safety assessment; dimethiconol esters; products used; reaction products; esters reaction

Journal Title: International Journal of Toxicology
Year Published: 2017

Link to full text (if available)


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