LAUSR

Background/Aims: To compare time tradeoff vision utilities from two developed Western countries to ascertain whether these vision-related, quality-of-life preferences are similar. Methods: Time tradeoff utilities were acquired from ophthalmology patient populations with ophthalmic pathologic conditions by personal interview in Italy and the United States using a reliable and previously validated, standardized questionnaire. Results: Data from 47 consecutive Italian participants and 325 consecutive American participants were compared. The populations were matched for gender, age, and ophthalmic pathologic conditions. The utilities for the various vision sub-cohort levels, characterized according to vision in the better-seeing eye for the Italian/American cohorts were as follows: (1) 20/20 sub-cohort, Italian/American mean utilities = 0.82/0.91 (p = 0.10); (2) 20/25–20/30 sub-cohort, Italian/American mean utilities = 0.79/0.86, (p = 0.05); (3) 2040–20/100 sub-cohort, Italian/American mean utilities = 0.76/0.74 (p = 0.70); and (4) 20/200 or less sub-cohort, Italian/American mean utilities = 0.66/0.58 (p = 0.58). Conclusion: Vision-related quality of life, as measured by time tradeoff utilities, was similar in Italian and American ophthalmic populations. This information is relevant when comparing quality of life and cost-utility analyses across international borders.