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Compelling evidence indicates that hippocampal dentate granule cells are generated throughout human life and into old age. While animal studies demonstrate that these new neurons are important for memory function,… Click to show full abstract
Compelling evidence indicates that hippocampal dentate granule cells are generated throughout human life and into old age. While animal studies demonstrate that these new neurons are important for memory function, animal research also implicates these cells in the pathogenesis of temporal lobe epilepsy. Several recent preclinical studies in rodents now suggest that targeting these new neurons can have disease-modifying effects in epilepsy.
Keywords:
epilepsy;
development epilepsy;
adult neurogenesis;
neurogenesis development
Journal Title: Epilepsy Currents
Year Published: 2019
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Journal Title: Epilepsy Currents
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!