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Drug-Induced Microbiome Changes: Considerations in Pregnancy

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During pregnancy, the maternal microbiome is associated with both the health of the mother as well as the developing fetus. Several classes of drugs are known to influence the microbiome… Click to show full abstract

During pregnancy, the maternal microbiome is associated with both the health of the mother as well as the developing fetus. Several classes of drugs are known to influence the microbiome and their use in pregnancy may impact maternal/fetal outcomes and long-term health of offspring. The drug-microbiome interactions of antibiotics, proton pump inhibitors, laxatives, metformin, and probiotics will be described, along with considerations for use of these agents in pregnancy.

Keywords: drug induced; induced microbiome; microbiome changes; considerations pregnancy; drug; changes considerations

Journal Title: American Journal of Lifestyle Medicine
Year Published: 2022

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