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3-Chloro-4-indolylmaleimides and two different alkynes are used as the starting materials in a novel and highly effective Pd-catalyzed addition/C–H activation/cyclization sequence for the synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones. The desired products are… Click to show full abstract
3-Chloro-4-indolylmaleimides and two different alkynes are used as the starting materials in a novel and highly effective Pd-catalyzed addition/C–H activation/cyclization sequence for the synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones. The desired products are obtained in moderate to excellent yields. Such compounds show a wide range of biological activities.
Keywords:
addition;
synthesis pyrrolo;
cyclization;
carbazole diones;
chloro indolylmaleimides;
pyrrolo carbazole
Journal Title: Journal of Chemical Research
Year Published: 2020
Link to full text (if available)
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Journal Title: Journal of Chemical Research
Year Published: 2020
Link to full text (if available)
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recommendations!