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A copper-catalyzed multicomponent cascade cyclization using readily available substrates, including 2-formylbenzonitriles, phenylacetylenes, and diaryliodonium salts, is achieved. A broad reaction scope is presented with good functional group compatibility, giving rise… Click to show full abstract
A copper-catalyzed multicomponent cascade cyclization using readily available substrates, including 2-formylbenzonitriles, phenylacetylenes, and diaryliodonium salts, is achieved. A broad reaction scope is presented with good functional group compatibility, giving rise to a range of 3-(2-oxopropyl)-2-arylisoindolinones in moderate to good yields.
Keywords:
oxopropyl arylisoindolinone;
reaction;
diaryliodonium salts;
synthesis oxopropyl;
formylbenzonitriles phenylacetylenes
Journal Title: Journal of Chemical Research
Year Published: 2022
Link to full text (if available)
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Journal Title: Journal of Chemical Research
Year Published: 2022
Link to full text (if available)
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recommendations!