Phytochemical examination of matured fruits of Rosa brunonii collected in Northern Pakistan led to the isolation of three flavonol glycosides quercetin-3-O-rhamnoside (1), and the kaempferol glycosides astragalin (2) and tiliroside… Click to show full abstract
Phytochemical examination of matured fruits of Rosa brunonii collected in Northern Pakistan led to the isolation of three flavonol glycosides quercetin-3-O-rhamnoside (1), and the kaempferol glycosides astragalin (2) and tiliroside (3). Their structures were elucidated by 1D– and 2D–NMR spectroscopy and mass spectrometry. Radical scavenging activities of the crude extract and isolated compounds were assessed by a DPPH assay. The results show strong antioxidative activities of tiliroside (3) and lower activities of astragalin (2) and quercetin-3-O-rhamnoside (1). These data confirm previous reports and underline the biological activities of flavonol glycosides.
               
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