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A new natural marine nor-sesquiterpenoid, (+)-pathylactone A (1), along with a know nor-sesquiterpenoid, napalilactoe (2), were isolated from the octocoral Paralemnalia thyrsoides. The structure of 1 was established on the… Click to show full abstract
A new natural marine nor-sesquiterpenoid, (+)-pathylactone A (1), along with a know nor-sesquiterpenoid, napalilactoe (2), were isolated from the octocoral Paralemnalia thyrsoides. The structure of 1 was established on the basis of spectroscopic methods and by comparison of the spectral data with those of synthetic analogues. Nor-sesquiterpenoid 1 was found to inhibit the protein experssion of pro-inflammatory inducible nitric oxide synthase (iNOS) in a murine macrophage-like cell line.
Keywords:
pathylactone new;
sesquiterpenoid octocoral;
paralemnalia thyrsoides;
new natural;
natural sesquiterpenoid;
octocoral paralemnalia
Journal Title: Natural Product Communications
Year Published: 2018
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Journal Title: Natural Product Communications
Year Published: 2018
Link to full text (if available)
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recommendations!