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A Short Step Conversion of Alkynyl Propargyl Sulfones into Six-Membered Cyclic β-Ketosulfones via an Amine-Induced Novel Ring Closure

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Alkynyl propargyl sulfones underwent secondary amine-induced cyclization to give six-membered cyclic enaminosulfones, and the products were subjected to acidic hydrolysis to afford the corresponding cyclic β-ketosulfones in high yields. Click to show full abstract

Alkynyl propargyl sulfones underwent secondary amine-induced cyclization to give six-membered cyclic enaminosulfones, and the products were subjected to acidic hydrolysis to afford the corresponding cyclic β-ketosulfones in high yields.

Keywords: propargyl sulfones; six membered; alkynyl propargyl; cyclic ketosulfones; membered cyclic; amine induced

Journal Title: Natural Product Communications
Year Published: 2018

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