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A new flavone, 5,4′-dihydroxy-7,3′-dimethoxy-6,8-dimethylflavone (1), together with four known compounds, ursolic acid (2), β-sitosterol-β-D-glucoside (3), β-sitosterol (4) and lupeol (5) were isolated from the methanolic extract of the leaves of… Click to show full abstract
A new flavone, 5,4′-dihydroxy-7,3′-dimethoxy-6,8-dimethylflavone (1), together with four known compounds, ursolic acid (2), β-sitosterol-β-D-glucoside (3), β-sitosterol (4) and lupeol (5) were isolated from the methanolic extract of the leaves of Astronia formosana. The structures were elucidated on the basis of physical and spectroscopic data analyses. Compound 1 showed the slight cytotoxicity against MCF-7, SCM-1, and SCC2095 cell lines with IC50 values of 29.3 ± 9.2, 20.5 ± 10.2, and 25.7 ± 2.9 μM, respectively.
Journal Title: Natural Product Communications
Year Published: 2018
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