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A new flavanone (2S)-7,4'-hydroxyl-6-(2″,3″-epoxy-3″-methylbutyl)flavanone (1), together with five known compounds (2–6) were isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic… Click to show full abstract
A new flavanone (2S)-7,4'-hydroxyl-6-(2″,3″-epoxy-3″-methylbutyl)flavanone (1), together with five known compounds (2–6) were isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity against α-glucosidase. Among them, new compound 1 was found to exhibit inhibitory activity on α-glucosidase with IC50 value of 29.2 μM.
Journal Title: Natural Product Communications
Year Published: 2018
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