LAUSR

The antioxidant and antifungal activity of n-hexane and ethyl acetate extracts of stems and roots of Jatropha dioica var. dioica, a plant species from the semi-arid regions of Hidalgo, Mexico, were evaluated by the 2,2-diphenyl-1-picrylhydrazyl and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) free-radical scavenging capacity assays and by growth inhibition of the phytopathogenic fungi, Alternaria alternata, Sclerotium rolfsii, Colletotrichum gloeosporioides, Rhizoctonia solani, and Fusarium oxysporum. The extracts exhibited a significant capacity to capture free radicals and a moderate capacity to inhibit fungal growth. A phytochemical study of these extracts led to the isolation of alkyl esters of acetic and ferulic acid, as well as the known diterpenes citlalitrione, jatrophatrione, jatropholone A, and jatropholone B, which were physically and spectroscopically characterized. These metabolites could be responsible for the observed antioxidant and fungicide activities of the extracts.