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A New Phenolic Diterpene From the Leaves of Rosmarinus officinalis

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As part of our continuous studies on dietary supplements for diabetes, 1 new phenolic diterpene, 7-butoxyrosmanol (1), and 3 known ones (2-4) were isolated from Rosmarinus officinalis. The new structure… Click to show full abstract

As part of our continuous studies on dietary supplements for diabetes, 1 new phenolic diterpene, 7-butoxyrosmanol (1), and 3 known ones (2-4) were isolated from Rosmarinus officinalis. The new structure was elucidated based on comprehensive spectroscopic methods, including multiple nuclear magnetic resonance techniques, mass spectrometry, and x-ray diffraction analysis. In addition, compound 1 showed moderate activity against pancreatic lipase with an IC50 value of 46.2 μM.

Keywords: diterpene leaves; officinalis new; rosmarinus officinalis; new phenolic; phenolic diterpene

Journal Title: Natural Product Communications
Year Published: 2022

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