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Novel imaging approaches for small animal models of lung disease (2017 Grover Conference series)

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Imaging in small animal models of lung disease is challenging, as existing technologies are limited either by resolution or by the terminal nature of the imaging approach. Here, we describe… Click to show full abstract

Imaging in small animal models of lung disease is challenging, as existing technologies are limited either by resolution or by the terminal nature of the imaging approach. Here, we describe the current state of small animal lung imaging, the technological advances of laboratory-sourced phase contrast X-ray imaging, and the application of this novel technology and its attendant image analysis techniques to the in vivo imaging of the large airways and pulmonary vasculature in murine models of lung health and disease.

Keywords: small animal; novel imaging; models lung; lung disease; animal models

Journal Title: Pulmonary Circulation
Year Published: 2018

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