Photo by rouichi from unsplash
We show that genetic deficiency of the reactive oxygen species generating enzyme NADPH oxidase 4 (NOX4) impairs hypoxic pulmonary vasoconstriction in small (25–40 µm) intra-acinar, but not pre-acinar, arteries in murine… Click to show full abstract
We show that genetic deficiency of the reactive oxygen species generating enzyme NADPH oxidase 4 (NOX4) impairs hypoxic pulmonary vasoconstriction in small (25–40 µm) intra-acinar, but not pre-acinar, arteries in murine precision cut lung slices. These data suggest an involvement of NOX4 in ventilation-perfusion matching at the acinar level.
Keywords:
pulmonary vasoconstriction;
intra acinar;
acinar;
nadph oxidase;
acinar arteries
Journal Title: Pulmonary Circulation
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Pulmonary Circulation
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!