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Fixed-Effect vs Random-Effects Models for Meta-Analysis: 3 Points to Consider

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Meta-analysis is the statistical procedure for combining data from multiple studies. Meta-analyses are being conducted with increasing frequency (Figure 1). Compared to a single clinical study, they can increase statistical… Click to show full abstract

Meta-analysis is the statistical procedure for combining data from multiple studies. Meta-analyses are being conducted with increasing frequency (Figure 1). Compared to a single clinical study, they can increase statistical power, improve accuracy, and provide a summary of fi ndings with respect to key clinical questions. Understanding the statistical models underlying the analysis is important.

Keywords: effect random; meta analysis; random effects; effects models; analysis; fixed effect

Journal Title: Global Spine Journal
Year Published: 2022

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