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Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis

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We report the case of a 71-year-old female who was incidentally found to have nonoliguric acute kidney injury on a routine workup for new-onset visual hallucination. Further history revealed inadvertent… Click to show full abstract

We report the case of a 71-year-old female who was incidentally found to have nonoliguric acute kidney injury on a routine workup for new-onset visual hallucination. Further history revealed inadvertent usage of nitrofurantoin for 3 months for an anticipated urological procedure. Renal biopsy demonstrated acute granulomatous interstitial nephritis. The renal function significantly improved following discontinuation of nitrofurantoin and corticosteroid administration. We highlight a rare association of nitrofurantoin with acute granulomatous interstitial nephritis through this case report.

Keywords: associated acute; interstitial nephritis; acute granulomatous; granulomatous interstitial; nitrofurantoin associated

Journal Title: Journal of Investigative Medicine High Impact Case Reports
Year Published: 2021

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